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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2798d450cfc04b212e60c8211066ec0a0c36bb6d3739446380a2fb3269f31ff' 
  AND token = '2I6ntOQc+fECS8lUggVpJOYzCxvMmHQbhT/34PRNFsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}