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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0b5b3af2731e5e642681151a863c549f17dd890330b61e914e55d439b87281f' 
  AND token = 'nuphtkb1zAu5cQ07UD69rAgwZm2RMP42hETLTJW/6Pg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}