SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '781e85e845645d9b938193b36c6398dc0d0dd35699ef0e889afddf03f3001fc6' 
  AND token = '7CfKxy8YZ2bjhTy1HPIQH2jYt7Pl8Rpq4hAirYUuvmI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}