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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe3145defa11fd5fa1a40aa89b6fc5ff0970c0a46eb4f394762637a5de12c328' 
  AND token = '9MYyhP0s6LSyhP1ZzhpBUNfStvrPtbTzJ0V+x9CRRvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}