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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4933cf1ae12f15c1b59e2cbe5bff535740c14130f880480b4141423802bdb73e' 
  AND token = 'qjH8shKZvnY1IAMjNf1h0Mj8IrCQN6btkAqX/OllcCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}