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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05c3f316ca3d0e67ac3b2e6cd8246a7f45b3cfa6a546179fede332353e395dfb' 
  AND token = 'G3RvZ/mNNqHJOETmPJRiXGd5elYEl+QuOu4VmwGlb4c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}