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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8de7223fdea06e5ad77d451c01e4e8f30a33152b3dbab12675bec3fd259a5c' 
  AND token = 'hp+59m1TvXj4RWwWvvBjTdis1sSp+BRO+mDIPcvLc2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}