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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49fa0f9b8b67e7224eef67b6101fbaff715a7c63b7f2391a4f5d6017f8a19525' 
  AND token = 'sWevoWXsIUWTU0s2FrJY2efrrUbIJgCy6DnD7icE+jc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}