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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a41c7d4518b1dedd364e6d746510de1fea2ef18f6542e3a556c5f0071465fd9' 
  AND token = 'TltVtqvYdoK/6n7r5Ois9Qsul5GP6j2ZUXgWxt/8SzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}