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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b6480d1f20144360d8ca8666493598f4678094da374195ce56bb56d73a71be7' 
  AND token = 'HGm6HGpiyZexkZcC23o0gr2Eh2jdeaXjrvDJdi0eMDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}