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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '306db790618b843cdf3e1ca5a7de0bb9d068094dbadb148f59ecc052bd7d86ed' 
  AND token = 'bU9F2qdnOrF0feas43rUIBSPEhEsSaavgdiQ7RxQ6yA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}