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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10e6c387934be2e379b9d03864b3295fd2b2fdcbdcb8cb6c7ec1ed80c2e79d8b' 
  AND token = 'rr8DDaEv6wExMPZOqHErfwH8f3bGDrSMGjKUizEx5Yw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}