SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e0a222efcf190c3d272a3351685dcc9fa9642a6496f5c67f528229d811f4d7' 
  AND token = '0sNP9j7WoJUR7qG1pV1rB/kWAOkP/ZJzZLFU0hjMk94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}