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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4bfa36c1fb3163b395fb90e82808b1b317f3bc8b72dbe021bdae1f7a39051ad' 
  AND token = '5GApaiuLb7ISr0k5qj44SjVzJO5DrlSfrtY5y+MbfUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}