SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee919bbc144bd19995c529ee731536a9cd438db1477feee9469939fd6055f352' 
  AND token = '0pPqy5z7vDHipk+1h071lvViOqoBhTYCADmpZUFjExY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}