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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c366211cf9b8cbded753004ba2a55bbabc62727a102660f4d6167f4a20b574c3' 
  AND token = 'ZkH+Dhz+NIx6nfW3FSRL7ae/86jvd/znzZa579nfRi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}