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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '99df09f79e1c915e6751b555d06362383737c8e173b2543f3d5003b14aa821f3' 
  AND token = 'E7c8Z9C3YfuL3iHlYQewAFAND0jI4M4iF1lfVHjEoi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}