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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81006bb29a375cba19a875fdd73d8683ffae0ecb5f6b583101b1d30484462aa2' 
  AND token = '449R2XWoikofa9PzSN84Xa+0uiZ5TxjJFqEK9SR1+no=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}