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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e47dd2036062d7c7ebd754a25fa1a43b6bf34efc25a953caa2cb738b38f1be38' 
  AND token = 'pyPUnKFF1n00LGGy0N9Ar/Dh9GFXMamrXk4cowAV9zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}