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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6dacfc599995512eb4f31b6500121aa117eadcbb84cc881b66081241702822ca' 
  AND token = 'zKcJXuX3ekbRkzp1nVWILTa2Xl75z4PDodpUP0sc+tE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}