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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fcd3d50cacf591c44bf6fd1e934f9b2458bf2eecd924e34aedc99b308feba11' 
  AND token = 'qIdRAXKEPpATt+KmP/I1N8Z/AyMJRpGuBfKA06tEb4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}