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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22eb216480d04e57c04e017235d9c08255cb3b5d0f0b9ca515ba3dd80baed03d' 
  AND token = 'NJbfdGIZqoBGipna3kabOtctp/X/prr0JBXLct9F1j0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}