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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea46740c72f0ffb899e003ab9701db07a1b318829597278359a25408d075511d' 
  AND token = '9MnhU3M4RxUYUFsSjiXPUvAPolQ9cc7b9KEn16EVE0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}