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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e60f7806d7b50e0ab0167b53b1d47c02ded6e4fe4442e1081800b6b2459b618b' 
  AND token = 'I2Lt/dIA162KBgpZUnuocdsoqAsZVbiAWzJCBFsfog0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}