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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b54db6f14a203be925bab4db69a4778dd507e7af1bb6d7a2f8357ca34cfc922' 
  AND token = '8OiElHio0t8+LzQ+1z+5rmC53+yfpPOqePYuhZ5egwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}