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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '234e6c7d6e56bc6c1aca90a72312fcabb53111221cf034ab4315e79ab4b3cc72' 
  AND token = '/JNOid8zuxwCbh5oeBgMTXKaNxuqVb4CNu5p1C8XLbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}