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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3142b36e14750e9388efb5b285d9317e726bc7f229d519fafdb095682439f8b6' 
  AND token = 'd7A1GXaaIttymN9bS6kdS7MI9dgPGBdIW5pBzMCGwus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}