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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2183e9f7252010d72686050224b5ed0488e16d923bd624ce6f92fa6bab7dc4b9' 
  AND token = '/oLPXMCpUI6JKDS1SY1AnftNOAF+KQxuOXDFGvy/8F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}