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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c2cc9b07466f7515504d599f7422c7608369256e47d29b2c1f9896cc269527' 
  AND token = 'VwuFF+o5ktJCPOGmc759u48uc+tqqLFbZjZaIyk/nWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}