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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '247eed6e4a9e77c748ae0e44801e4c871cb3e7d495dc2171e286bebf9dae0adc' 
  AND token = 'e6ZTa54MlBYZpBpCuYer+qhNAzQMgO1i1wrC19zz8GA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}