SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9925690cc5613531c6bed0e060a544b9a2619c0d92c1a224d9601f31bdd9ff51' 
  AND token = 'W8I3ARRJ7Hh9eTSBEhU1B/MS6tdSHYw00e8A+vD16pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}