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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9cc8f22775108bd7e0d6de91f817a196eb5bb1518343b3bf9a902fbc14017d11' 
  AND token = 'Zb360MeNGq5nfgT00jV7Rzo3XBq4ANpIMmX26VGZNlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}