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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fce8da921812aade7f3d12427d5d4110f4b673760a9e4f5008dced6910d7e245' 
  AND token = 'V8dG8Rf7GiFXccM/ov6IJsn4TJFHhHCjfBomftBUah0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}