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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3161aead24b1532f1f1e39f90c186a9ea12edf01e0f218a64f5b8a93b1b2f6a' 
  AND token = 'A8GmG1kHRhrvRRlXb4X7PQ2m7DGgKA0gOptVBoUHYdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}