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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4506b84ac4c9dc5946bd0cf6295e495f98adbb5481087b215d4ec0b2c8d1eaf5' 
  AND token = 'k6A1QhHBkqGXaj8YDdFn0cfQ71OJqQn4r0iDoRAgBcg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}