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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec1da659e8f39ff970a41c581a17566f51fc46b1d136eaa772b9fae7778a6d9d' 
  AND token = 'tpwCCICKRNR+PRNVMCMRXs7Rv6rcxWXDHmtUX4q2wDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}