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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a3d1f778ca60a9701f24d44c66c0d313881dcec5929fccfe33d8262af9fa49' 
  AND token = 'AfGS4hN3ToOXsiMh9jRIbm4kCqEw9ItaC5qp7L+C3P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}