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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bde6f4671c85324f4855345b1b080b8b0408fef383d1e52a2375daca89dbdb2a' 
  AND token = 'zPQ3R0ikqzOmqJ9B7tknpwPHviX41AJopJ/1JMmSSEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}