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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cb2bd5d812625e386d315dab23a505659974c33437ee700cb0e9f5755100c27' 
  AND token = 'GLLlv67o3gnC1eNEYL/zrh6jx3tLY6Eez7/ZrSwMmms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}