SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08bfae4a9bd522d70c106b4826bbaea4298cb7e5ba105c2c2320098001ec6b0f' 
  AND token = 'UMjKLvpm7XVrdKRpNVJlTPqW1+DsAqfuHsN3EC0CKYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}