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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd6053c5852f4aba1f30a2143e0dec76a7d72d0f87e7fe333b59d58c7e663f4d' 
  AND token = '+S6oYUkkBUA65PuAbRX52qgUOyrKxp+YTXwTmhwx8Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}