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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c7634060192b8c1b964d37ac8bdc803a650a03148e33968b25b599f24ba1385' 
  AND token = 'yOUlCjqHrXs+gTLAsGDv6nhRI9ktZNd/xD9g29Yt/14=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}