SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53e1d5b06a18541e4e646c571a75789f7f2e518aa8aaf12d5dceff3af9943b5' 
  AND token = 'diWslDLaMSYWSI2f4fgo6HLubmDoX0e96yGJ7TSohc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}