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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1eed5c6d7286e6d499bc4adc5129246d950e4a32930a5a7a6565fd987f37b11' 
  AND token = 'yaN+VOpDIEviOIE3jAwLABqmIO8UwE0WwFHl56n/37Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}