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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07176251bebefaf667412c0c46b941555143615dd581d5fcf4fb4df1be5c8b37' 
  AND token = 'Ot1a1w9/jw2YRroVh3m8L2u3HgMmeuqMfCpHkd7uLUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}