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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14f016d73460584ad149a095a26e7a786ca123130b3b11b710b716272ddc196c' 
  AND token = 'JLcEXMsOhQGBbEmBcKRiBHuEOf/DeVzSWOxf03Wg5SQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}