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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca1893c11021012a1aba0a42b28d086497e405049e46837cfb0332c83a362cc0' 
  AND token = '9btoXZQgKvu2RGVCXTKphZAbDweao+eXuIJ/e2DR4pY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}