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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '787d795a490dd3fba373b19390c5d5d1424f4ba1a734c578c3fbde192ebd6b3c' 
  AND token = 'wUh5nHtBWLLetSwfJCN61yVmPCo0RYJsEV9W8qRZ6qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}