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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c659bab07f2625439650ee2b416ad69baff8b3a37fe9e3e8417dbf6b1eec3dd' 
  AND token = 'iQKdGZyKnm45Qsr2Fpxd8Els8mDwSfV9Rrxj8Zd8MGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}