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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c82bd9385eb14d1a26ac43b8f639e0efecea7b66c15f67bd95af82cb35037722' 
  AND token = 'N5JeA5EXGdI6R85aFS0VwDvZl8GJBLnKtgUU26fmFGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}